Our Research Team are experts in the field of breast cancer research and they work tirelessly to help us achieve our goal of preventing breast cancer for future generations.

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    Keith is a Professor of Developmental Signalling at The University of Manchester. His interests lie in how cells of the breast communicate with each other during its development and turnover of breast cells with the menstrual cycle and pregnancy. He is particularly interested in understanding how this communication breaks down leading to breast cancer and whether understanding these processes can point to new therapies. He is currently researching how cell communication changes with increasing breast density to see whether this can shed more light on how high breast density predisposes women to breast cancer.

    For more information about Prevent Breast Cancer’s current research projects, click here.

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    Professor Evans leads Prevent Breast Cancer’s genetic research. He has established a national and international reputation in clinical and research aspects of cancer genetics, particularly in breast cancer and neurofibromatosis.

    He has published 555 peer-reviewed research publications and 80 reviews/chapters. He has an ISI web of knowledge, H-index of 76 and google scholar of 100. In the last 5 years he has raised over £10 million in grants for multicentre and local studies. He has led a successful bid for a Nationally funded NF2 service (£7.5 million pa) that started in 2010.

    For more information about Professor Evans’ research click here.

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    Ashu has expertise in breast reconstruction surgery, and along with surgeons Barr, Johnson and Rose is part of our clinical team who provide risk-reducing mastectomy surgery to our Family History Clinic.

    Ashu’s current Genesis research project is “Patient Related Outcome Measures and Surgical Outcomes in High Risk Women”.

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    James specialises in breast reconstruction and is also involved in research into breast cancer and breast reconstruction. James’ interests include increasing access to breast reconstruction and improving the quality of life for women choosing reconstructive surgery. James is also Chair of our Medical Advisory Board (MAB) and a member of the Genesis Scientific Advisory Board (SAB).

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    Dr Michelle Harvie is an award-winning research dietitian funded by Prevent Breast Cancer. For the last 22 years she has specialised in optimum diet and exercise strategies for weight loss and preventing breast cancer and its recurrence. Her findings have been published in many major scientific journals. Dr Harvie is the author of the best-selling book The 2-Day Diet. Click here for more information about her research.

    She was awarded the British Dietetic Association Rose Simmond’s Award for best published dietetic research in 2005, Manchester City Council’s 2007 International Women’s Day Award for Women in Science, and the National Association for the Study of Obesity Best Practice Award for best published obesity research in 2010.

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    Professor Tony Howell is Genesis’ Scientific Director. He is also a Professor of Medical Oncology at The University of Manchester. Tony has specialised in treating breast cancer for over 30 years and now focuses on pharmacological and lifestyle measures to prevent breast cancer. He is Chairman of several international breast trials and is the former Chairman of the UK Breast Trials organisation (UKCCCR), the British Breast Group and the ATAC trial. Up to the end of 2007, Tony was the Research & Development Director of The Christie NHS Foundation Trust and Research Director of the Greater Manchester & Cheshire Cancer Research Network. He is also the former Director of the Breakthrough Breast Cancer Research Unit, and the Manchester Breast Centre. Tony was the Chief Investigator of the IBIS-II Prevention Study.

    Tony enjoys lecturing internationally and has had published over 600 scientific papers and book chapters, mainly concerning the biology of the breast and the treatment and prevention of breast cancer. Click here to read more about our research projects.

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    A Consultant Breast Radiologist at the Nightingale Centre, Anil also holds honorary professor post at the University of Salford and honorary senior lecturer post at the University of Manchester. He is a member of the Cancer Prevention and Early Detection Strategic Group at NHS England Greater Manchester. Anil chairs the Asian Breast Cancer Support Group and leads the Cross Cultural Communication Skills training programme since 2011.

    Dr Jain is spearheading the breast cancer awareness campaign especially in ethnic minority and deprived communities. His research interests include comparative study of various aspects of breast cancer in Asian and Caucasian women; barriers to breast screening uptake and solutions to them and investigating usage of multimedia tablets in breast screening vans & static units raising awareness about breast screening, mammography and assessment processes.

    Besides Prevent Breast Cancer, Anil has attracted grants from NHS England Greater Manchester and Sheffield Hallam University. Anil was awarded life Fellowship of BMA in 2013, HSJ Top 50 BME Pioneer Award 2014 and Health and Social Care BME Network Embrace Award in 2015 for outstanding service and promoting equality and diversity in the NHS.

    For more information about our Asian Women’s Health Awareness project, click here.

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    Cliona is part of the Consultant Breast team at UHSM but in addition is a Research Scientist with a particular interest in how breast cancer can affect blood clotting mechanisms and how this phenomenon might lead to new blood tests for cancer or even new treatments. Cliona is also the Chair of our Scientific Advisory Board (SAB) and a member of our Medical Advisory Board (MAB).

    Click here to read more about Cliona’s current research.

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    Tony is a Consultant Breast Radiologist. His interests include the prevention, early diagnosis and follow-up of breast cancer, pre-invasive breast disease, breast imaging technology and minimally invasive techniques for diagnosis and treatment. He is currently leading a Prevent Breast Cancer funded study looking at tomosynthesis in breast cancer screening (a new 3D mammography technique) and is conducting a study on MRI assessment of pre-invasive breast cancer. Tony is also an active collaborator on several other major studies.

    For more information about the Tomosynthesis study (FH Tomo), click here.

     

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    A Professor of Translational Genomic Medicine at the University of Manchester and Consultant in Genetics at St Mary’s Hospital. Professor Newman is keen to see how genetic discoveries can be used for patient benefit. He is the lead of the Greater Manchester 100,000 Genome Medicine Centre using genome sequencing and the current Chair of the British Society of Genetic Medicine. He has used new genetic technologies to discover the causes of over 12 rare inherited conditions.

    Bill works closely with Professor Gareth Evans on a number of breast cancer-related projects. He has been funded by Genesis to see how variants that are common in the population can increase some women’s risk of breast cancer and how this information may be used to tailor their care more effectively.

    Click here for more information about our Gene Research.

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    A Professor of Cell Biology at the University of Manchester. Charles was awarded a Senior Research Fellowship in Basic Biomedical Science by the Wellcome Trust to set up his own laboratory in 1992. He jointly established the Manchester Breast Centre in 2005 and co-founded the Breakthrough Breast Cancer Research Unit at the University of Manchester in 2009. He was appointed to the position of Director of the Wellcome Trust Centre for Cell-Matrix Research from 2009 until 2014.

    Charles’ scientific achievements have been to discover mechanisms by which cell adhesion controls developmental morphogenesis, survival and proliferation, as well as tissue-specific gene expression in epithelia. By focusing on mammary gland, he revealed the central role of integrin adhesion receptors in mammalian cell behaviour, providing a general framework for understanding epithelial tissue development and function.

    For more information about Genesis’ current research projects, click here.