Our Impact

ResearchSince 1996, Prevent Breast Cancer has been working hard to eradicate breast cancer for future generations. We’re so proud of what we have achieved and want to thank everyone who has supported us in making such incredible impact. Below you can find our Annual Report & Financial Statement, as well as some of our achievements to date.


Annual Report & Financial Statement


Every year we produce an Annual Report & Financial Statement to showcase the achievements of the charity and the research teams associated with Prevent Breast Cancer. You can read this year’s full report by clicking here.

Our clinical investigators are located at the Prevent Breast Cancer Research Unit in The Nightingale Centre at Wythenshawe Hospital, while other investigators feed into the prevention programme from The Manchester Cancer Research Centre at The Christie and departments on the main university site. In addition we have several national and international research collaborations, principally with Professor Jack Cuzick in London and Professor Doug Easton in Cambridge. To find out more about our experts, click here.


Our Achievements include…

  • Founding Europe’s first breast cancer prevention centre, The Nightingale Centre and Prevent Breast Cancer Research Unit, based at Manchester Foundation Hospital NHS Trust in partnership with the NHS. This world-class facility, the largest Breast Centre in the UK, leads the way in breast cancer early diagnosis and research.
  • Discovering a previously undetected fault in the BRCA1 gene which increases the risk of breast cancer.
  • Our scientists have conducted The Prediction of Cancer at Screening Study (PROCAS), the largest recruiting research study in Britain, involving 57,000 women.
  • Trialling breast screening tailored to individual risk, a new approach that could revolutionise breast screening across the UK.
  • Identifying over 300 of the fragments of DNA which affect breast cancer risk and developed a simple saliva test to detect them and help determine the risk calculation for each woman.
  • Studying ductal carcinoma-in-situ (DCIS), a form of non-invasive breast cancer commonly detected at screening, to better understand what conditions lead DCIS to develop into higher grade cancers and help doctors determine which women need surgery to prevent invasive cancer.
  • Being one of the first research groups to find that weight loss can reduce the risk of breast cancer. In our study of 34,000 women modest weight loss i.e. losing 10 pounds of weight reduced risk by 25-40%.
  • Publication of The 2-Day Diet, Cookbook and Quick & Easy edition continues to increase awareness of our vital work and send a positive health message across the UK and the world. To date over 340,000 copies have sold in the UK and the diet was published in over 16 countries.
  • Establishing the 2 Day Diet Club, spearheaded by our supporters and with over 300 members currently.
  • Delivering Health Hour talks on breast awareness and how to reduce your risk to organisations and their staff.
  • Publishing over 170 research papers between August 2015 and September 2019.
  • Participating in MyPeBs, an international EU-funded clinical study that evaluates a new breast cancer screening strategy.
  • Presenting our research all over the world including at the San Antonio Breast Cancer Symposium in the US.
  • Forming part of a group of 10 experts who met to draw up a “Gap Analysis” of our knowledge concerning breast cancer and breast biology. The resulting paper identified major gaps, and was published to wide acclaim in “Breast Cancer Research” in September 2014.
  • Publishing “The Angelina Effect”, a paper describing how referrals to our own and other Family History Clinics and Genetic Centres doubled as a result of publicity surrounding Angelina Jolie’s decision to have risk-reducing breast surgery after the discovery that she carries a mutation in the BRCA1 gene. Most of the referrals were judged to be appropriate indicating an unfulfilled need for services for women at a very high risk. The paper had the highest data analysis score for any paper ever published by the “Breast Cancer Research” journal.
  • Launching Update Hours, a series of free online events on subjects including ‘The impact of the pandemic on breast cancer’,’ How we are working to prevent breast cancer now and in the future’, ‘Diet and lifestyle’ and ‘The menopause’, which have been accessed and viewed by hundreds of people.
  • Taking the Boo-Bee Bus across the city of Manchester during Breast Cancer Awareness Month to raise awareness and distribute information in locations where screening uptake is lower than the national average.
  • Launching the ‘It’s Time for You’ campaign and website in partnership with Hologic to raise awareness of the importance of breast cancer screening among women aged 50-71.


And we won’t stop there..

Prevent Breast Cancer is the only UK charity entirely dedicated to the prediction and prevention of breast cancer – we’re committed to freeing the world from the disease altogether. Unlike many cancer charities, we’re focused on preventing, rather than curing. Promoting early diagnosis, screening and lifestyle changes, we believe we can stop the problem before it starts. And being situated at the only breast cancer prevention centre in the UK, we’re right at the front-line in the fight against the disease.

Join us today and help us create a future free from breast cancer. If you have any questions or concerns, email info@preventbreastcancer.org.uk today.